Drug delivery from holding chambers with attached facemask.

Jet nebulizers versus pressurized metered dose inhalers with valved holding chambers: effects of the facemask on aerosol delivery.

The delivery of an aerosolized drug to a child is a complex process requiring an interaction between parent, child, and inhalation device. Recent studies have shown that the facemask can be a key factor affecting aerosol delivery, particularly the influence of leaks between the facemask and the face. To further quantify these effects and design around them, we have developed a bench model consi...

AeroChamber* Brand of Valved Holding Chambers

Dead space variability of face masks for valved holding chambers.

BACKGROUND Valved holding chambers with masks are commonly used to deliver inhaled medications to young children with asthma. Optimal mask properties such as their dead space volume have received little attention. The smaller the mask the more likely it is that a greater proportion of the dose in the VHC will be inhaled with each breath, thus speeding VHC emptying and improving overall aerosol ...

Niosomes from Preparation to Application in Drug Delivery

Introduction: In recent years, the treatment strategy for infectious and autoimmune diseases has significantly changed. Up to now, cancer treatment has been conducted on the basis of clinical and pathological methods. The most common cancer treatments is limited to chemotherapy, radiation therapy and surgery. However, cancer treatment is still not optimal. Common challenges for treatment of cer...

A three-dimensional mathematical model for drug delivery from drug-eluting stents

Current drug-eluting stent (DES) technology is not optimized with regard to the pharmacokinetics of drug release, more research on the <span style="font-size: 12pt; color: #000000; font-style: normal; ...